Paraytec is a UK based scientific instrument company manufacturing and distributing a wide range of products for pharmaceutical and biopharmaceutical applications.
Our patented ActiPix™ technology is a 2-dimensional detection platform for UV-Vis absorbance measurement, using capillaries or area detection in conjunction with sophisticated optics and active pixel area sensors.
The ActiPix™ D100 is a powerful area imaging detector enabling multiplex detection for the research and OEM community. The small footprint enables easy integration into a variety of high throughput microfluidic systems.
The TDA200 enables rapid determination of hydrodynamic radius using only 100 nanolitres of samples. It is ideal for sizing proteins and antibodies in pure or aggregated forms in filtered or unfiltered samples. It is an ideal benchtop tool for bioformulations groups.
The SDI300 enables intrinsic dissolution rate for sparingly soluble APIs in less than 10 minutes using less than 10 mg of sample. The UV camera also gives valuable mechanistic detail about the process of dissolution directly at the dissolving surface. It can be used in a variety of areas including APIs, stents, gels, pastes, suspensions, dental erosion, transdermal patches. It is ideal for the pre-formulations community.
“I have been using ActiPix™ for more than two years, since the early stage of its development. From the beginning, it became clear to me that this miniature detector provides exceptional flexibility which is crucial when solving complex analytical problems. ActiPix™ enables UV monitoring of multiple sections of single capillaries and in parallel channels. This greatly enhanced throughput and resolution of biochemical assays carried out in the ‘lab-on-capillary©’ format. For example, it was straightforward to set up protocols for the assessment of substrate specificities of different enzymes. Velocities of species originating from anywhere within the capillary could precisely be measured facilitating this way comprehensive analysis of the in-capillary reactions and separations. I was astonished to see how easy it was to connect ActiPix™ to standard analytical instruments. I have no doubts that, due to its unique features, ActiPix™ will act as an ‘enabling technology’ to support future research endeavours in the broad field of bioscience.”
"The ActiPix™ D100 is the perfect system for us. The extremely high sensitivity, ease of use and direct potential for high throughput made it hugely attractive and directly relevant to our application in microcapillary biocatalysis."
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